Information retrieval systems support users in finding relevant information in data sets. List layouts are wide-spread, but spatial layouts are catching up. User studies that systematically show their benefits for users are missing. We report on a comparative between-subject study with 43 participants comparing a spatial layout with a list layout. One group performed a task with a system providing semantic visualization, and the other group performed the same task with a system without semantic visualization. The results show that the users of the spatial layout had significantly more interaction with the system in shorter time, with a slightly higher outcome and higher satisfaction.