To improve healthcare professionals’ health and wellbeing at work, many available effective treatments including meditation, and workplace intervention, have been developed. However, the utilisation of these interventions is still limited. Currently, various mobile health applications (mHealth Apps) exist to help a wide range of users with different occupational health issues, such as stress, anxiety, and burnout. Despite their advantages, post-download uptake of mHealth apps by end-users remains low. Some of the reasons for this are poor usability, irrelevant or missing user-desired features, and poor user experience. This review paper explores the usefulness of mHealth Apps for the early detection of occupational-related ill-health among healthcare workers. Science Direct, ACM Digital Library, IEEE Xplore, and SAGE Journal were searched comprehensively to identify relevant research articles. A total of 9546 reviewed papers were primarily identified through the systematic search on the databases. 2546 articles were removed from them, by duplication check on a RefWorks software. Titles and abstract screening of the remaining 126 led to 50 relevant articles being selected for full text screening. Of these 76 were excluded based on exclusion criteria. Finally, 19 articles were selected for a final inclusion to identify the relevant usefulness design goals, including usability, utility and user experience, deemed as critical for apps’ adoption and use. These goals include provide contextually relevant information, which is easy to understand for usability; support self-help guidance and in-depth knowledge for occupational health and wellbeing for utility: reinforced trust and perceived security in m-Health apps for user experience.