The context of use plays an important role in Human-Centered Software Engineering (HCSE). Typically, user, environment, and platform are considered to make up the core aspects of the context of use. Changing the context of use has significant impact on how to design and develop with a user-centered perspective and how usage of these systems changed for example in the current pandemic situation with a focus on remote work. New kinds of work environments in industry providing different types of user assistance evolve, new settings for remote and distributed work styles are required to account for social distancing, or the trends towards autonomous and AI-based systems demand for new ways of thinking about socio-technical interaction and systems. This workshop promotes sharing of knowledge and experiences that address how to deal with evolving contexts of use in today’s and future application domains and its influence on human-centered socio-technical system design and development practices. Beyond the traditional themes of IFIP Working Group 13.2 workshops, the main focus lies on theories, methods, and approaches for dealing with the context of use, its influence on HCSE, and factors for its change over time.