The problem of protecting datasets from the disclosure of confidential information, while published data remains useful for analysis, has recently gained momentum. To solve this problem, anonymization techniques such as k-anonymity, $$\ell $$ℓ-diversity, and t-closeness have been used to generate anonymized datasets for training classifiers. While these techniques provide an effective means to generate anonymized datasets, an understanding of how their application affects the performance of classifiers is currently missing. This knowledge enables the data owner and analyst to select the most appropriate classification algorithm and training parameters in order to guarantee high privacy requirements while minimizing the loss of accuracy. In this study, we perform extensive experiments to verify how the classifiers performance changes when trained on an anonymized dataset compared to the original one, and evaluate the impact of classification algorithms, datasets properties, and anonymization parameters on classifiers’ performance.