This paper introduces digital solutions for manufacturing repurposing transformations that address the impact of COVID19 on production operations. The paper outlines how different Industry 4.0 solutions can be combined in a unified platform for manufacturing repurposing. Emphasis is paid on introducing worker and Operator 4.0 related solutions, including tools for plant risk assessment, shifts allocation, context-aware reskilling of employees and remote support processes. The latter are essential elements of a strategy for exploiting automation and Artificial Intelligence (AI) systems during COVID19 times and future healthcare crises.