This research is based on the recent endeavors of the manufacturers to achieve improvements in supply chain resiliency by implementing Industry 4.0 standards. The large enterprises, in today’s scenario, are pursuing their supplier organizations to incorporate information and communication technology (ICT) based advancements to their production systems. But successful implementation of such technologies in the resource deficient supplier organizations depends on several factors that need due consideration of the decision makers. In this paper, we have identified 14 such critical success factors from extant literature for implementation of technologies conforming to Industry 4.0. Further, through an empirical investigation comprising of 222 micro, small and medium enterprises (MSMEs) from the automotive manufacturing sector in India, we have made use of exploratory factor analysis and structural equation modelling to identify the hidden constructs and examine the influencing relationships between them.