Supply Chain (SC) uncertainty perspectives must now be translated into practice. SC entities must accept crises and catastrophes as normal situations and increase significantly their culture of SC risk management. They should adapt their decision-support systems to be able considering disruptions as regular inputs, whether small, large or huge. Collaboration should not be limited to few entities of a SC, but to the whole SC. Concrete tools allowing entities to share vital information to give visibility, ensure synchronization of the material flows, align management of emergencies and use of critical resources must be developed and used. That is the purpose of this paper. Practically, aframework for SC risk and opportunity management and a Collaborative and Open Supply Chain Management Operating Services (COSMOS) platform are presented. An illustrative case is developed to highlight the potential benefits of the proposal on one service example.