The benefits of Model-Based Definition (MBD) are well known. Considering this there is a need to understand the reasons why MBD is utilized rarely in the manufacturing ecosystems of low volume, customized products. For studying MBD, manufacturing ecosystems and their mutual relations a literature study and a case study of manufacturing ecosystem were applied. It was noticed that there are differences between the maturities of digital product processes between the actors of the ecosystem, while MBD itself is a matter affecting the whole ecosystem. Investing in education and renewing, integrating and harmonizing processes, legacy data and software lower barriers towards adopting MBD. The motivation of the actors of an ecosystem has to ensure investments and commitment to change. The investment decisions require an ecosystem wide value definition and business case for each actor. The role of an actor within an ecosystem, how common or niche the utilized product and production technology is and the economic situation of a company appear to impact companies’ willingness to change into MBD. Also, the motivation to adopt MBD depends on the amount of legacy data and the complexity of manufactured parts. Adopting PMI-data can increase the efficiency of manufacturing processes, such as quality control.