Bridging different worlds of meaning, overcoming disciplinary borders and expanding horizons of theoretical and practical knowledge is the task of semiotics, in general, and of social semiotics, in particular. The role of the present paper is to question the emergence of information sciences’ new paradigms through the use of philosophically grounded constructs. The argument is: contemporary societies, and the organisations they host, are bounded by thought and action mind frames, which practical philosophy is able to address, to identify and to make explicit. Heidegger’s mastery work has set in motion a tradition which enables the design and exploration of the bridges between three different worlds: first, data science and its computing science paradigms; second, social semiotics, and its contribution to the understanding of meaning-making; and third, e-leadership, as a practical application of the fundamental ideas and concepts that are transversal to diverse disciplinary areas and that capture business making fundamentals.