Engineer-to-order products are customized to a particular client’s specification. Planning can be a problem as the products may be large and complex especially due to uncertainties in the duration of the operations. A conceptual project manufacturing planning and control (PMPC) framework is presented in relation to typical engineer to order (ETO) companies. The existing approaches, problems, solutions, and limitations of current manufacturing planning and control (MPC) for ETO environment are discussed. This paper contributes to the development of an improved understanding and more robust definition of MPC in ETO industries, and highlights how the key challenges and the opportunities that PMPC offer in an ETO sector.